Thermo Fisher Scientific JPO2/RAM2 Polyclonal Antibody
JPO2/RAM2 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human 시료에 반응합니다. Western blot 및 Immunoprecipitation에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 4°C에서 보관합니다.
- 카탈로그번호
- A300846A
- 판매단위
- pk
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Thermo Fisher Scientific JPO2/RAM2 Polyclonal Antibody
Applications
- Western Blot (WB): 1:2,000–1:10,000
- Immunoprecipitation (IP): 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 400 and the C-terminus (residue 454) of human c-Myc interacting protein JPO2 (transcription factor RAM2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Cell division cycle-associated 7-like protein (RAM2) is a transcription factor involved in transcriptional regulation and apoptotic signaling pathways.
It acts as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to its promoter.
RAM2 plays an oncogenic role in mediating the transforming effect of MYC in medulloblastoma cells and may act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3, CCND1/cyclin D1, and E2F1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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