Thermo Fisher Scientific JPO2/RAM2 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human JPO2/RAM2 (CDCA7L) region 400–454. Validated for WB and IP. Unconjugated liquid form, 0.2 mg/mL concentration. Suitable for research use in transcriptional regulation and apoptosis studies.
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Thermo Fisher Scientific JPO2/RAM2 Polyclonal Antibody
Applications and Tested Dilutions
- Western Blot (WB): 1:2,000–1:10,000
- Immunoprecipitation (IP): 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 400 and the C-terminus (residue 454) of human c-Myc interacting protein JPO2 (transcription factor RAM2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
Target Information
Cell division cycle-associated 7-like protein (RAM2) is a transcription factor involved in transcriptional regulation and apoptotic signaling. It acts as a repressor inhibiting MAOA activity and gene expression by promoter binding. RAM2 plays an oncogenic role by mediating MYC’s transforming effect in medulloblastoma cells and may act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3, CCND1/cyclin D1, and E2F1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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