Thermo Fisher Scientific HADHA Polyclonal Antibody
Human 및 Mouse에 반응하는 Rabbit Polyclonal HADHA 항체로, Western Blot, IHC, ICC 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보존. 장기 보관 시 -20°C에서 저장 권장.
- 카탈로그번호
- PA553317
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human HADHA. Recombinant protein control fragment (Product #RP-91063) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2642299 |
Product Specific Information
Immunogen sequence:
IEYLEEVAIT FAKGLADKKI SPKRDKGLVE KLTAYAMTIP FVRQQVYKKV EEKVRKQTKG LYPAPLKIID VVKTGIEQGS DAGYLCESQK FGELVMTKES KALMGLYHGQ VLCKKNKFGA PQKDVKHLAI LGAGLMGAGI AQVSVDK
Highest antigen sequence identity to the following orthologs:
- Mouse: 86%
- Rat: 85%
Target Information
This gene encodes the alpha subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long-chain fatty acids.
The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the alpha subunit catalyzing the 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities.
Mutations in this gene result in trifunctional protein deficiency or LCHAD deficiency.
The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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