Thermo Fisher Scientific HADHA Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

Immunogen sequence:
IEYLEEVAIT FAKGLADKKI SPKRDKGLVE KLTAYAMTIP FVRQQVYKKV EEKVRKQTKG LYPAPLKIID VVKTGIEQGS DAGYLCESQK FGELVMTKES KALMGLYHGQ VLCKKNKFGA PQKDVKHLAI LGAGLMGAGI AQVSVDK

Highest antigen sequence identity to the following orthologs:

• Mouse: 86%
• Rat: 85%

Target Information

This gene encodes the alpha subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long-chain fatty acids.
The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the alpha subunit catalyzing the 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities.
Mutations in this gene result in trifunctional protein deficiency or LCHAD deficiency.
The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.