Thermo Fisher Scientific FANCI Polyclonal Antibody
FANCI 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 사용 가능. 인간 시료 반응성, 항원 친화 정제, PBS/glycerol buffer 보존. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human KIAA1794 (Recombinant protein control fragment, Product #RP-105985) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2664944 |
Product Specific Information
Immunogen sequence:
YYLQVCQSSGG IPKNMEKLVK LSGSHLTPLC YSFISYVQNK SKSLNYTGEK KEKPAAVATA MARVLRETKP IPNLIFAIEQ YEKFLIHLSK KSKVNLMQHM KLSTSRDFKI KGN
Highest antigen sequence identity to the following orthologs:
- Mouse: 81%
- Rat: 82%
Target Information
The Fanconi anemia complementation group (FANC) includes FANCA, FANCB, FANCC, FANCD1 (BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (BRIP1), FANCL, FANCM, and FANCN (PALB2).
Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair.
The members of the FANC group assemble into a common nuclear protein complex. This gene encodes the protein for complementation group I, with alternative splicing producing two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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