Thermo Fisher Scientific GLB1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:4,000

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human beta Galactosidase. Recombinant protein control fragment (Product #RP-104284). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:beta Galactosidase,uniProtId:P16278-1,ncbiNodeId:9606,antigenRange:589-677,antigenLength:677,antigenImageFileName:PA5-65272_beta_Galactosidase_P16278-1_Rabbit.svg,antigenImageFileNamePDP:PA5-65272_beta_Galactosidase_P16278-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2662594

Product Specific Information

Immunogen sequence: GRYWPARGPQL TLFVPQHILM TSAPNTITVL ELEWAPCSSD DPELCAVTFV DRPVIGSSVT YDHPSKPVEK RLMPPPPQKN KDSWLDHV

Highest antigen sequence identity to the following orthologs - mouse 47%, rat 46%.

Target Information

Beta Galactosidase encodes a member of the glycosyl hydrolase 35 family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature lysosomal enzyme. This enzyme catalyzes the hydrolysis of a terminal beta-linked galactose residue from ganglioside substrates and other glycoconjugates. Mutations in this gene have been associated with GM1-gangliosidosis and Morquio B syndrome. Diseases associated with GLB1 include Gm1-Gangliosidosis, Type I and Gm1-Gangliosidosis, Type Ii.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.