Thermo Fisher Scientific TOLLIP Polyclonal Antibody
Rabbit 폴리클로날 항체로 인간 및 비인간 영장류 TOLLIP 단백질 검출에 적합함. Western blot에서 1:1,000 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태. 보존제 없음, -20°C 보관. 연구용으로만 사용.
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues surrounding cysteine 229 of human Tollip |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.01M HEPES (pH 7.5), 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10988658 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses.
TLRs act through adaptor molecules to activate various kinases and transcription factors, allowing the organism to respond to potential infection. These adaptor molecules include TOLLIP, MyD88, and TRIF.
TOLLIP associates directly with TLR2 and TLR4, acting as an inhibitor to TLR activation. This negative regulation of TLR signaling may serve to limit the production of proinflammatory mediators during infection and inflammation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- PA5-17384_TOLLIP_Q9H0E2-1_Rabbit.svg
- PA5-17384_TOLLIP_Q9H0E2-1_Rabbit_PDP.jpeg
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