Thermo Fisher Scientific IL36B Polyclonal Antibody
Mouse IL36B/IL1F8 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC 및 ELISA에 적합. 보존제가 없는 액상 형태로 제공되며, 장기 보관 시 -20°C 권장. NF-kappaB 경로 연구 및 면역반응 분석에 활용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Mouse IL36B/IL1F8 Protein (Met1–Lys183) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788626 |
Product Specific Information
- Preservative-free formulation. It is recommended to add sodium azide (final concentration 0.05%–0.1%) to prevent contamination.
- This antibody specifically recognizes Mouse IL36B/IL1F8.
Target Information
IL-36B is a member of the interleukin 1 cytokine family located within a cytokine gene cluster on chromosome 2.
It is known to activate the NF-kappaB pathway via IL-1 receptor family members IL-1RL2 and IL-1RAcP.
Similar to IL-36A and IL-36G, IL-36B requires post-translational processing for full agonist activity, though the cleavage mechanism remains unknown.
IL-36 cytokines are suggested to amplify Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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