Thermo Fisher Scientific Human JAKMIP2 Synthetic Peptide

Applications

Control (Ctrl)

• Assay-dependent

Blocking Assay (BLOCK)

• Assay-dependent

Product Specifications

Product Specific Information

This peptide corresponds to 16 amino acids near the center of human JAKMIP2.
PEP-1538 can be used as a blocking peptide with polyclonal antibody PA5-34496.

Target Information

JAKMIP2 (janus kinase and microtubule-interacting protein 2), also known as NECC1 (neuroendocrine long coiled-coil protein 1), CTCL tumor antigen HD-CL-04, JAMIP2 or KIAA0555, is an 810 amino acid protein belonging to the JAKMIP family.
Localizing to the Golgi apparatus, JAKMIP2 is highly expressed in the brain, with moderate expression in thymus, spleen, and lung.
It exists as three alternatively spliced isoforms.
The gene encoding JAKMIP2 maps to human chromosome 5q32 and mouse chromosome 18 B3. Chromosome 5 contains 181 million base pairs and comprises nearly 6% of the human genome.
Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.