Thermo Fisher Scientific Human JAKMIP1 Synthetic Peptide
인간 JAKMIP1 중심부 16개 아미노산 서열 기반 합성 펩타이드로, PA5-34495 항체의 블로킹 실험에 사용 가능. 정제된 액상 형태이며 PBS 완충액에 0.1% BSA 포함. 신경 및 림프 세포에서 발현되는 JAKMIP1 연구용으로 적합.
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Thermo Fisher Scientific Human JAKMIP1 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the center of human JAKMIP1.
PEP-1537 can be used as a blocking peptide with polyclonal antibody PA5-34495.
Target Information
JAKMIP1, also known as Marlin-1, is a highly conserved vertebrate-specific microtubule-associated protein that plays a role in JAK1 signaling and regulates microtubule cytoskeleton rearrangements.
JAKMIP1 is expressed predominantly in neuronal and lymphoid cells and colocalizes with microtubules.
Multiple isoforms of JAKMIP1 are known to exist: isoforms 1 and 5 are also expressed in liver, lung, and skeletal muscle, while isoforms 2–4 are specifically expressed in brain and retina.
JAKMIP1 participates in polarized secretion in lymphocytes and has been suggested to be a novel effector memory gene restraining T cell-mediated cytotoxicity.
Dysregulation of JAKMIP1 gene expression is associated with genetic conditions linked to autism in humans.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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