Thermo Fisher Scientific PDGFRB Monoclonal Antibody (K.596.7)
PDGFRB 단일클론 항체(K.596.7)는 Human, Mouse, Rat에 반응하며 Western blot, IP 등 다양한 응용에 적합합니다. 비교활성이 없으며 액상 형태로 제공됩니다. 연구용으로만 사용되며 높은 특이성과 안정성을 제공합니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PDGFRB Monoclonal Antibody (K.596.7)
Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunocytochemistry (ICC/IF) | - | View 1 publication |
| Immunoprecipitation (IP) | 1:50 | - |
| Functional Assay | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | K.596.7 |
| Immunogen | Recombinant human PDGF receptor β protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.75 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20 °C |
| Shipping Conditions | Wet ice |
| RRID | AB_10979500 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with PDGF receptor-alpha.
Target Information
PDGFRB is a receptor tyrosine kinase implicated in atherogenesis and cell transformation by the SIS oncogene. These growth factors act as mitogens for mesenchymal-origin cells. The bound growth factor determines whether the receptor forms a homodimer or heterodimer composed of PDGF receptor alpha and beta polypeptides. The PDGFRB gene is located on chromosome 5 near the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor, which may be associated with the 5-q syndrome. A translocation between chromosomes 5 and 12 fusing PDGFRB (CD140b) with ETV6 results in chronic myeloproliferative disorder with eosinophilia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.