Thermo Fisher Scientific IBP160 Polyclonal Antibody, Biotin
Thermo Fisher Scientific의 IBP160 Polyclonal Antibody는 Biotin으로 표지된 Rabbit IgG 항체로, Human, Mouse, Rat에 반응합니다. Western blot, ELISA, Immunoprecipitation에 사용 가능하며, pre-mRNA splicing 관련 단백질 AQR을 타겟으로 합니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 1:50–1:250
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 1250–1300 on human RNA helicase Aquarius protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Involved in pre-mRNA splicing as a component of the spliceosome (PubMed:11991638, PubMed:25599396, PubMed:28502770, PubMed:28076346).
Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP biogenesis (PubMed:16949364).
Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly (PubMed:16949364).
May act by helping the folding of the snoRNA sequence.
Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during late stages of splicing (PubMed:16949364).
Has ATP-dependent RNA helicase activity and can unwind double-stranded RNA molecules with a 3′ overhang (in vitro) (PubMed:25599396).
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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