
Thermo Fisher Scientific Phospho-ATF2 (Ser498) Polyclonal Antibody
Phospho-ATF2 (Ser498) 폴리클로날 항체로, 인간 및 생쥐 시료에서 ATF2 인산화 단백질 검출에 적합합니다. Western blot과 IHC(파라핀 절편)에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 고순도(>95%), 1 mg/mL 농도의 액상 형태로 제공됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide derived from human ATF2 around the phosphorylation site of Serine 498 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2553731 |
Product Specific Information
- Detects endogenous ATF2 protein at a molecular weight of 55–75 kDa.
- Purity >95% by SDS-PAGE.
Target Information
ATF-2 (also known as CRE-BP1) is a transcription factor that binds to AP-1 and CRE DNA response elements and belongs to the ATF/CREB family of leucine zipper proteins.
It interacts with viral oncoproteins and tumor suppressors and is a target of SAPK/JNK and p38 MAP kinase signaling pathways.
Cellular stress such as genotoxic agents, inflammatory cytokines, and UV irradiation activate ATF-2 transcriptional activity via phosphorylation at Thr69 and Thr71.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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