Thermo Fisher Scientific SERCA3 ATPase Polyclonal Antibody
Rabbit polyclonal antibody recognizing human SERCA3 ATPase. Validated for IHC (paraffin) at 1:50–1:200. Antigen affinity purified, supplied in PBS with 40% glycerol. Suitable for research use in calcium pump and SERCA family studies.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SERCA3 ATPase. Recombinant protein control fragment (Product #RP-88662). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2647136 |
Product Specific Information
Immunogen sequence:
SRDRKSMSVY CTPTRPHPTG QGSKMFVKGA PESVIERCSS VRVGSRTAPL TPTSREQILA KIRDWGSGSD TLRCLALATR DAPPRKEDME LDDCSKFVQY E
Highest antigen sequence identity to the following orthologs:
- Mouse: 90%
- Rat: 89%
Target Information
ATP-dependent calcium pumps are responsible in part for maintaining low cytoplasmic free calcium concentrations. These pumps, located in intracellular organelles, are encoded by a family of structurally related enzymes known as the sarcoplasmic or endoplasmic reticulum calcium ATPases (SERCA).
The SERCA2 gene undergoes tissue-dependent processing, producing the SERCA2a isoform (expressed in muscle tissues) and the SERCA2b isoform (expressed in all cell types).
SERCA3 co-expresses with SERCA2b in platelets, mast cells, lymphoid cells, and epithelial cells, and is referred to as the non-muscle form of SERCA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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