Thermo Fisher Scientific TSHZ3 Polyclonal Antibody
TSHZ3 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC에 적합합니다. 인간, 생쥐, 랫드 반응성을 가지며, 항원 친화 크로마토그래피로 정제되었습니다. 냉장 보관(2–8°C) 권장, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (IHC) | 2.5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | An 18 amino acid synthetic peptide near the amino terminus of human TSHZ3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551696 |
Product Specific Information
- A suggested positive control is mouse brain tissue lysate.
- PA5-34344 can be used with blocking peptide PEP-1387.
Target Information
The Teashirt zinc finger homeobox (TSHZ) family comprises evolutionarily conserved transcription factors. In Drosophila, these factors are involved in body patterning, while in vertebrates, their roles are less defined. In mice, TSHZ proteins are expressed in distinct brain regions, suggesting a role in regional identity and neuronal cell type specification.
TSHZ3 and TSHZ1 interact with FE65, an adapter protein that binds to the amyloid precursor protein (APP) in neurons. Together with SET and histone deacetylases, they form a gene-silencing complex targeting caspase-4. Recent studies suggest potential involvement of this family in carcinogenesis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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