Thermo Fisher Scientific CNTF Polyclonal Antibody
CNTF 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, ICC/IF, ELISA에 사용 가능. 인간, 마우스, 랫트 반응성. 액상 형태, 0.64 mg/mL 농도, -20°C 보관. 신경세포 생존 관련 연구에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 24–74 of human CNTF (NP_000605.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.64 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914239 |
Product Specific Information
- Positive test controls: Mouse skeletal muscle
- Subcellular location: Cytoplasm
Immunogen sequence:
ARKIRSDLTA LTESYVKHQG LNKNINLDSA DGMPVASTDQ WSELTEAERL Q
Target Information
The CNTF protein is a polypeptide hormone primarily active in the nervous system, promoting neurotransmitter synthesis and neurite outgrowth. It acts as a survival factor for neurons and oligodendrocytes and may help reduce tissue destruction during inflammatory attacks. Mutations causing aberrant splicing lead to CNTF deficiency, though not directly linked to neurologic disease. A read-through transcript variant with ZFP91 and CNTF sequences has been identified but is considered non-coding.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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