Thermo Fisher Scientific MVP/Major Vault Protein Polyclonal Antibody
Thermo Fisher Scientific의 MVP/Major Vault Protein 다클론 항체로, 인간 단백질에 반응하며 WB, IHC, IP 등에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 항체로 1 mg/mL 농도. 약물 내성 연구 및 세포 단백질 발현 분석에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:2,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 843 to 893 of human Major Vault Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan
Target Information
This gene encodes the major vault protein, a lung resistance-related protein. Vaults are multi-subunit structures possibly involved in nucleo-cytoplasmic transport. The protein mediates drug resistance, potentially via a transport process. It is widely distributed in normal tissues and overexpressed in multidrug-resistant cancer cells. Overexpression may serve as a useful marker of clinical drug resistance. Two transcripts are produced using alternative exon 2 sequences; both share the same open reading frame.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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