Thermo Fisher Scientific NTSR2 Polyclonal Antibody
Human NTSR2 단백질을 인식하는 Rabbit Polyclonal Antibody. IHC(P) 및 ELISA에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 항체로, 1 mg/mL 농도. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 10 µg/mL |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 20 amino acid peptide from internal region of human NTSR2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550414 |
Product Specific Information
- Percent identity with other species by BLAST analysis:
Human, Gibbon (100%); Monkey, Bovine, Dog, Pig (95%); Marmoset, Mouse, Rat (90%); Hamster (85%); Rabbit (80%) - For IHC(P), use proteinase K antigen retrieval.
- After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
The protein encoded by this gene belongs to the G protein-coupled receptor family that activates a phosphatidylinositol-calcium second messenger system.
Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands described for the neurotensin NT1 receptor.
Unlike NT1 receptor, this gene recognizes with high affinity levocabastine, a histamine H1 receptor antagonist that competes with neurotensin for low-affinity binding sites in the brain.
These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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