Thermo Fisher Scientific OLFM4 Polyclonal Antibody
OLFM4 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간 OLFM4 내부 서열 기반 면역원 사용. IHC(Paraffin) 검증 완료. 암 연구 및 세포 분화 관련 연구용으로 적합. 연구용으로만 사용 가능.
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Thermo Fisher Scientific OLFM4 Polyclonal Antibody
Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 10–15 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from internal region of human OLFM4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550415 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset (100%)
Guinea pig (94%)
Orangutan, Rat, Hamster, Dog, Rabbit (88%)
Target Information
OLFM4 is a 510 amino acid extracellular matrix glycoprotein belonging to the olfactomedin-related protein family and found to be selectively expressed in inflamed colonic epithelium. It has one signal peptide, six N-linked glycosylation motifs, and forms disulfide-bonded multimers.
OLFM4 may have a matrix-related function in differentiation and is constitutively expressed in cancer cells, where it binds to the apoptosis inducer GRIM-19, exhibiting antiapoptotic activity and serving as a potential diagnostic marker for human cancers.
Reports suggest that OLFM4 promotes proliferation of PANC-1 cells by favoring transition from the S to G2/M phase. Potential interactions with endogenous cell surface lectins and cadherins may mediate cell adhesion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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