
Thermo Fisher Scientific IFIT1 Polyclonal Antibody
Mouse IFIT1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot에 최적화되어 있습니다. ISG56(p56) 검출에 사용되며 항바이러스 RNA 결합 단백질 연구에 적합합니다. 액상 형태로 제공되며 -20°C에서 보관합니다.
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Thermo Fisher Scientific IFIT1 Polyclonal Antibody
Applications
- Western Blot (WB): Assay-dependent
- View 3 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | aa 217–233 of mouse IFIT1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_1958734 |
Product Specific Information
PA3-846 detects ISG56 (p56) from mouse samples.
PA3-846 has been successfully used in Western blot applications to detect a 39–58 kDa band.
Target Information
Interferon-induced antiviral RNA-binding protein that specifically binds single-stranded RNA bearing a 5′-triphosphate group (PPP-RNA). Acts as a sensor of viral single-stranded RNAs and inhibits expression of viral messenger RNAs.
Single-stranded PPP-RNAs, lacking 2′-O-methylation of the 5′ cap, serve as viral signatures to distinguish between self and non-self mRNAs during infection.
Viruses may evade this system by encoding their own 2′-O-methylase or by “cap snatching” host mRNAs.
Exhibits antiviral activity against several viruses including human papilloma and hepatitis C viruses.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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