Thermo Fisher Scientific GPX4 Polyclonal Antibody
GPX4 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF 등 다양한 응용에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 고순도의 친화 크로마토그래피 정제 제품입니다. 세포 내 산화 손상 연구에 활용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 2 publications |
| Immunohistochemistry (IHC) | – | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | – |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | – |
Product Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GPX4 (Accession P36969), corresponding to amino acid residues I170–F197. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851923 |
Product Specific Information
This antibody detects endogenous levels of total GPX4.
Target Information
Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage.
Human plasma glutathione peroxidase is a selenium-containing enzyme where the UGA codon is translated into selenocysteine.
Through alternative splicing and transcription initiation, rat produces proteins localized in the nucleus, mitochondrion, and cytoplasm.
In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and cleavage sites of mitochondrial and nuclear transit peptides require further verification.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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