Thermo Fisher Scientific Dysferlin Polyclonal Antibody
Thermo Fisher Scientific Dysferlin Polyclonal Antibody는 인간 Dysferlin 단백질을 인식하는 Rabbit IgG 항체로, WB, IHC, Flow Cytometry에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 근위부 근이영양증 연구에 적합. 장기보관 시 -20°C 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein within human Dysferlin (aa 124–317) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS (pH 7.4) with 50% Glycerol, 0.2% BSA |
| Contains | 0.05% Sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at −20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2802725 |
Target Information
Dysferlin is the protein product of the 2p13 gene, which is defective in patients with Limb-Girdle Muscular Dystrophy type 2B (LGMD2B) and Miyoshi Myopathy (MM). Dysferlin is normally localized to the muscle plasma membrane. In patients with LGMD2B and MM, immunoreactivity to dysferlin is severely reduced or lost depending on the mutation type. This antibody is used for the characterization of LGMD2B and MM.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-85924_Dysferlin_O75923-1_Rabbit_PDP.jpeg, PA5-85924_Dysferlin_O75923-1_Rabbit.svg)
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