Thermo Fisher Scientific KLK8 Monoclonal Antibody (OTI1G9), TrueMAB
Human KLK8 단백질(아미노산 33-260)에 특이적으로 반응하는 마우스 단클론 항체. Western blot에 최적화된 TrueMAB 형식. 무보존제, 동결건조 형태로 제공되며 재구성 및 결합 실험에 적합. 암 및 질병 바이오마커 연구용.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 33–260 of human KLK8 produced in SF9 cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Kallikreins are a subgroup of serine proteases with diverse physiological roles. Many are implicated in carcinogenesis and serve as potential biomarkers for cancer and other diseases.
KLK8 is one of fifteen kallikrein subfamily members located in tandem on chromosome 19. It may participate in proteolytic cascades in the skin and act as a biomarker for ovarian cancer.
Alternate splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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