Thermo Fisher Scientific PCCA Polyclonal Antibody
Thermo Fisher Scientific의 PCCA Polyclonal Antibody는 인간 Propionyl-CoA carboxylase alpha chain을 인식하는 닭 유래 IgY 항체입니다. Western blot에 사용 가능하며, 미토콘드리아 내 효소 연구에 적합합니다. 장기 보관 시 -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Chicken / IgY |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to human Propionyl-CoA carboxylase alpha chain (Mitochondrial) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2158549 |
Product Specific Information
By Western blot, this antibody has only been tested on fusion protein.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This protein is a key enzyme in the catabolic pathway of odd-chain fatty acids, isoleucine, threonine, methionine, and valine.
It is probably a dodecamer composed of six biotin-containing alpha subunits and six beta subunits.
The protein is located in the mitochondrial matrix.
Defects in PCCA are the cause of propionic acidemia type I (PA-1).
PA-1 is a life-threatening disease characterized by episodic vomiting, lethargy and ketosis, neutropenia, periodic thrombocytopenia, hypogammaglobulinemia, developmental retardation, and intolerance to protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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