Thermo Fisher Scientific PTP1B Polyclonal Antibody
Thermo Fisher Scientific의 PTP1B Polyclonal Antibody는 인간 PTPN1 단백질을 인식하는 닭 유래 IgY 항체입니다. Western blot에 최적화되어 있으며, 1:2,000 희석 비율로 사용됩니다. 액상 형태로 제공되며, 단기 4°C, 장기 -20°C 보관이 권장됩니다. 연구용 전용 제품입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Published species | Rat |
| Host / Isotype | Chicken / IgY |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to human Receptor-type tyrosine-protein phosphatase T |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2173106 |
Product Specific Information
By Western blot, this antibody has only been tested on fusion protein.
Target Information
PTP1B (PTPN1) is a tyrosine-protein phosphatase that acts as a regulator of the endoplasmic reticulum unfolded protein response. It mediates dephosphorylation of EIF2AK3/PERK and inactivates the protein kinase activity of EIF2AK3/PERK. PTP1B also participates in CKII- and p60c-src-induced signal transduction cascades and regulates the EFNA5-EPHA3 signaling pathway, influencing cell reorganization and cell-cell repulsion. Additionally, PTP1B modulates hepatocyte growth factor receptor signaling through dephosphorylation of MET.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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