Thermo Fisher Scientific IL17C1 Polyclonal Antibody, FITC
IL17C1 단백질을 표적으로 하는 FITC 결합 폴리클로날 항체입니다. Western blot, ELISA, Immunoprecipitation 등에 사용 가능하며, 인간 및 비인간 영장류 반응성을 가집니다. 고순도 친화 크로마토그래피 정제 제품으로 연구용에 적합합니다.
- 카탈로그번호
- IL17RC1-FITC
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific IL17C1 Polyclonal Antibody, FITC
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:1,000
- ELISA: 1:10,000
- Immunoprecipitation (IP): 1:50–1:250
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 70–120 on IL17RC1 protein common to C2 and C5 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Receptor for IL17A and IL17F, major effector cytokines of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity.
Acts as receptor for IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RA. Also binds IL17A–IL17F heterodimer and IL17F homodimer, triggering downstream TRAF6 and NF-κB signaling.
Induces transcriptional activation of IL33, promoting group 2 innate lymphoid cells and Th2 cell responses.
Stimulates sympathetic innervation of peripheral organs and thermogenic adipose tissue.
Binding of IL17A–IL17F to IL17RA–IL17RC complex activates TRAF6-mediated NF-κB and MAPK pathways, resulting in cytokine and chemokine production.
Primarily induces neutrophil activation and antimicrobial peptide expression by epithelial cells.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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