Thermo Fisher Scientific MAP3K10 Polyclonal Antibody, Biotin

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1:10,000

-

Immunoprecipitation (IP)

1:50-1:250

-

Dot blot (DB)

1:10,000

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Chicken / IgY

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide correpsonding to the C-terminal taken within amino acid region 900-950 on human MAP3K10 protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MLK2,uniProtId:Q02779-1,ncbiNodeId:9606,antigenRange:900-950,antigenLength:954,antigenImageFileName:MAP3K10-Y-BIOTIN_MLK2_Q02779-1_Chicken.svg,antigenImageFileNamePDP:MAP3K10-Y-BIOTIN_MLK2_Q02779-1_Chicken_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Biotin Biotin Biotin

Form

Liquid

Concentration

0.5-1.5 mg/mL

Purification

Affinity chromatography

Storage buffer

proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

MAP3K10 (MLK2) is a serine/threonine kinase which has been shown to activate MAPK8/JNK and MKK4/SEK1. This kinase itself can be phoshorylated, and is thus activated by JNK kinases. MAP3K10 functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.