
Thermo Fisher Scientific PADI4 Monoclonal Antibody (OTI4H5)
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Applications
Tested Dilution
Publications
Western Blot (WB)
1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
1:150
Immunocytochemistry (ICC/IF)
1:100
Flow Cytometry (Flow)
1:100
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse / IgG2a
Class
Monoclonal
Type
Antibody
Clone
OTI4H5
Immunogen
Full length human recombinant protein of PADI4 produced in HEK293T cell if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
PADI4,
uniProtId:
Q9UM07-1,
ncbiNodeId:
9606,
antigenRange:
1-663,
antigenLength:
663,
antigenImageFileName:
MA5-25986_PADI4_Q9UM07-1_House_mouse.svg,
antigenImageFileNamePDP:
MA5-25986_PADI4_Q9UM07-1_House_mouse_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2723438
Target Information
Catalyzes the citrullination/deimination of arginine residues of proteins. Citrullinates histone H3 at Arg-8
and/or Arg-17
and histone H4 at Arg-3
, which prevents their methylation by CARM1 and HRMT1L2/PRMT1 and represses transcription. Citrullinates EP300/P300 at Arg-2142
, which favors its interaction with NCOA2/GRIP1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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