Thermo Fisher Scientific ACBD3 Monoclonal Antibody (OTI3E7)
ACBD3 단백질을 표적하는 Thermo Fisher Scientific의 마우스 단일클론 항체입니다. Western blot, IHC, Flow cytometry에 적합하며, 고순도 친화 크로마토그래피 정제 제품입니다. PBS/BSA/glycerol 완충액에 보관되며 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3E7 |
| Immunogen | Full-length human recombinant ACBD3 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723826 |
Target Information
GOLPH1, also known as GCP60, is a Golgi protein that interacts with the integral membrane protein giantin and plays a role in maintaining Golgi structure.
It also interacts with Golgin-160, which can be cleaved by caspases-2, -3, and -7, leading to nuclear localization of Golgin-160 fragments.
GOLPH1 interaction with these fragments is regulated by the oxidation state of Cys-463, indicating that Golgi fragmentation and reconstitution may regulate Numb signaling and couple cell fate with cell cycle progression.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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