Thermo Fisher Scientific KCNT1 Polyclonal Antibody
KCNT1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. Western blot과 IHC에 사용 가능. 인간 및 비인간 영장류 반응성. 합성 펩타이드 항원 기반, 동결건조 형태. 연구용으로만 사용.
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Thermo Fisher Scientific KCNT1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:3,000 |
| Immunohistochemistry (IHC) | 1:3,000 |
| Miscellaneous PubMed (Misc) | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Published species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human KCNT1 conjugated to blue carrier protein was used as the antigen |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage buffer | Whole serum |
| Contains | No preservative |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: KCNT1
Target Information
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include:
- Regulating neurotransmitter release
- Heart rate control
- Insulin secretion
- Neuronal excitability
- Epithelial electrolyte transport
- Smooth muscle contraction
- Cell volume regulation
This gene encodes a sodium-activated potassium channel subunit involved in ion conductance and developmental signaling pathways.
Mutations in this gene cause early-onset epileptic disorders such as malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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