Thermo Fisher Scientific FGFR4 Polyclonal Antibody
FGFR4 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western Blot, IHC, Flow Cytometry에 적합. 인간 및 생쥐 반응성. KLH 결합 합성 펩타이드 면역원 사용. 고순도 정제 및 안정적 저장 조건 제공.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Flow Cytometry (Flow) | 1:10–1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 24–55 amino acids from the N-terminal region of human FGFR4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation, Size-exclusion, Dialysis |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2103673 |
Target Information
FGFR4 is a member of the FGFR family of receptor tyrosine kinases, which regulate various cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair. The FGFR family is implicated in diseases such as cancer, rheumatoid arthritis, and diabetic retinopathy. FGFR4 is required for normal down-regulation of CYP7A1 expression, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. It also plays a role in postnatal lung development and skeletal muscle cell lineage formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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