Thermo Fisher Scientific Caspase 10 Polyclonal Antibody
Rabbit polyclonal antibody targeting human Caspase 10. Validated for Western blot applications. Supplied as an unconjugated liquid form at 1 mg/mL concentration. Suitable for apoptosis and caspase pathway research. For research use only.
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Thermo Fisher Scientific Caspase 10 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution
- 1:100–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide containing amino acids 505–521 of Human Caspase 10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_1016743 |
Target Information
This gene encodes a protein that belongs to the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes that undergo proteolytic processing at conserved aspartic residues to produce two subunits (large and small), which dimerize to form the active enzyme. Caspase 10 cleaves and activates caspases 3 and 7 and is itself processed by caspase 8. Mutations in this gene are associated with apoptosis defects observed in type II autoimmune lymphoproliferative syndrome. Three alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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