Thermo Fisher Scientific Phospho-MARCKS (Ser152, Ser156) Polyclonal Antibody
MARCKS 단백질의 Ser152/156 인산화 형태를 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합. Mouse와 Rat에 반응하며, 액상 형태로 제공. 단백질 인산화 연구 및 신호전달 분석에 유용.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-MARCKS (Ser152, Ser156) Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
- View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser152/156 of rat MARCKS conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2234991 |
Product Specific Information
This antibody is predicted to react with bovine, chicken, human, mouse, Xenopus, and zebrafish based on 100% sequence homology.
It specifically detects the ~87 kDa MARCKS protein phosphorylated at Ser152 and Ser156 in Western blots of rat brain homogenates.
Immunolabeling is blocked by the phosphopeptide used as the antigen but not by the corresponding dephosphopeptide.
Target Information
MARCKS is a substrate for protein kinase C and is localized to the plasma membrane as an actin filament crosslinking protein.
Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and the plasma membrane, resulting in cytoplasmic localization.
The protein plays roles in cell motility, phagocytosis, membrane trafficking, and mitogenesis.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.