Thermo Fisher Scientific SLC8A2 Polyclonal Antibody
Rabbit polyclonal antibody targeting human SLC8A2 protein. Validated for IHC (Paraffin) with 1:25–1:100 dilution. Detects endogenous total SLC8A2. Supplied in PBS with 40% glycerol, 0.05% sodium azide. For research use only.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific SLC8A2 Polyclonal Antibody
Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:25–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region derived from internal residues of human solute carrier family 8 (sodium/calcium exchanger), member 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636011 |
Product Specific Information
This antibody detects endogenous levels of total SLC8A2 protein.
Target Information
Sodium/calcium exchanger proteins are integral membrane proteins primarily found in cardiac cells. In cardiac myocytes, Ca²⁺ concentration alternates between low levels during relaxation and high levels during contraction. The Na⁺/Ca²⁺ exchanger 1 (NCX1) mediates Ca²⁺ extrusion during relaxation. Four NCX1 isoforms (NCX1.1, NCX1.3, NCX1.7, NCX1.10) result from alternate splicing. NCX1 mRNA is highly expressed in the heart and at lower levels in the brain. NCX2 is most abundantly expressed in the brain, while NCX1 shows broader distribution in heart, kidney, lung, and muscle tissues. These expression patterns suggest distinct functional roles for each subtype. Regulatory mechanisms of these exchangers remain incompletely characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.