Thermo Fisher Scientific CCBL1 Polyclonal Antibody
Thermo Fisher Scientific의 CCBL1 Polyclonal Antibody는 인간, 마우스, 랫트 시료에서 Western blot 및 Immunocytochemistry에 사용됩니다. Rabbit에서 유래한 비결합형 항체로, 항원 친화 크로마토그래피로 정제되었습니다. PBS/glycerol 완충액 형태로 제공되며, 연구용으로만 사용 가능합니다.
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- PA576025
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:10–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human CCBL1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719753 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
Kynurenine aminotransferases (KAT I, KAT II, and KAT III) belong to the class-I pyridoxal-phosphate-dependent aminotransferase family.
KAT I is a cytoplasmic protein involved in glutamine catabolism and catalyzes the transamination of L-kynurenine to form kynurenic acid, a neuroprotective and anticonvulsant metabolite of tryptophan.
Kynurenic acid plays a role in synaptic transmission and is implicated in neurological disorders such as schizophrenia and Huntington’s disease.
KAT I also metabolizes cysteine conjugates of halogenated alkenes and alkanes to form reactive metabolites.
Isoform 1 is the full-length protein, isoform 2 lacks amino acids 68–117, and isoform 3 lacks amino acids 251–422. Based on sequence similarity, KAT I is thought to function as a homodimer.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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