Thermo Fisher Scientific GPR32 Polyclonal Antibody
Human GPR32 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 및 ELISA에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 20 µg/mL |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 15 amino acid peptide from C-terminus of human GPR32 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550285 |
Product Specific Information
- Percent identity with other species by BLAST analysis: Human (100%); Marmoset (87%)
- For IHC(P), use heat-induced antigen retrieval in pH 6.0 citrate buffer.
- After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
The G-protein-coupled receptor (GPCR) superfamily consists of approximately 600–1,000 members and represents the largest known class of molecular targets with therapeutic potential.
The intronless GPR32 gene encodes an orphan G protein-coupled receptor that binds to resolvin D1 and lipoxin A4.
Resolvin D1 binding to GPR32 is associated with the resolution of pulmonary inflammation and suppression of TGFβ-induced epithelial-mesenchymal transition in A549 lung cancer cells.
Resolvins are being explored as potential therapeutics that act during the resolution phase of chronic inflammation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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