Thermo Fisher Scientific GPR32 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

20 µg/mL

-

ELISA (ELISA)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic 15 amino acid peptide from C-terminus of human GPR32. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GPR32,uniProtId:O75388-1,ncbiNodeId:9606,antigenRange:356,antigenLength:356,antigenImageFileName:PA5-32823_GPR32_O75388-1_Rabbit.svg,antigenImageFileNamePDP:PA5-32823_GPR32_O75388-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.1% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2550285

Product Specific Information

Percent identity with other species by BLAST analysis: Human (100%); Marmoset (87%).

For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Target Information

The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. The intronless GPR32 gene encodes an orphan G protein-coupled receptor that binds to resolvin D1 and lipoxin A4. Resolvin D1 binding to GPR32 has been linked to resolution of pulmonary inflammation, suppression of TGFbeta induced epithelial mesenchymal transition of A549 lung cancer cells. Resolvins are being evaluated as new drug candidates acting at the resolution phase of chronic inflammation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.