Thermo Fisher Scientific IGFBP7 Monoclonal Antibody (1D9E7)
IGFBP7 단백질을 인식하는 마우스 단일클론 항체로, Western blot, IHC, ELISA에 사용 가능. 정제된 재조합 인간 IGFBP7 단편(aa 52-156)을 면역원으로 사용. 단백질 G로 정제된 액상 형태이며, 1 mg/mL 농도로 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1D9E7 |
| Immunogen | Purified recombinant fragment of human IGFBP7 (aa: 52–156) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4 °C short term. For long term, store at −20 °C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898455 |
Product Specific Information
This antibody has been tested in indirect ELISA.
Target Information
The IGFBP7 gene encodes a member of the insulin-like growth factor (IGF)-binding protein family. IGFBPs bind IGFs with high affinity and regulate IGF availability in body fluids and tissues, modulating IGF binding to its receptors.
IGFBP7 binds IGF-I and IGF-II with relatively low affinity and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion.
Alternatively spliced transcript variants encoding different isoforms have been described, and one variant has been associated with retinal arterial macroaneurysm.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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