Thermo Fisher Scientific TTLL12 Monoclonal Antibody (OTI3H6), TrueMAB
TTLL12 단백질을 표적으로 하는 Mouse IgG2a 모노클로날 항체. Western blot, IHC, ICC/IF, Flow cytometry 등 다양한 응용 가능. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도 유지. 종 특이성: Dog, Human, Rat.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Dog, Human, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3H6 |
| Immunogen | Full length human recombinant protein of human TTLL12 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional round of desalting (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
TTLL12 (tubulin tyrosine ligase-like family, member 12) is a 644 amino acid protein containing one TTL domain.
Among the fourteen TTLL family members that modify tubulin, TTLL12 is the least characterized.
It is highly expressed in metastatic prostate cancer cell lines and considered a potential target for tumor therapy.
Overexpression of TTLL12 may alter chromosome ploidy, while downregulation affects post-translational modifications of tubulin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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