Thermo Fisher Scientific TTLL12 Monoclonal Antibody (OTI4E3), TrueMAB
TTLL12 단백질을 표적으로 하는 Mouse IgG2a 단클론 항체로 다양한 응용 분야(WB, IHC, ICC, Flow)에 사용 가능. 고순도 친화 크로마토그래피 정제, 무보존제, 동결건조 형태로 제공. 암 연구 및 세포 단백질 발현 분석에 적합.
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Thermo Fisher Scientific TTLL12 Monoclonal Antibody (OTI4E3), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4E3 |
| Immunogen | Full-length human recombinant TTLL12 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
TTLL12 (tubulin tyrosine ligase-like family, member 12) is a 644 amino acid protein containing one TTL domain. Among the fourteen TTLL family members that modify tubulin, TTLL12 is the least characterized. It is highly expressed in metastatic prostate cancer cell lines and considered a potential target for tumor therapy. Overexpression of TTLL12 may alter chromosome ploidy, while downregulation affects post-translational modifications of tubulin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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