
Thermo Fisher Scientific Synaptophysin (Neuroendocrine Marker) Monoclonal Antibody (rSYP/4654)
신경내분비 표지자 Synaptophysin을 검출하는 Mouse monoclonal 항체. IHC(P) 및 IHC(PFA)에서 사용 가능하며, 인간 시료에 반응. 단백질 A/G로 정제된 액상 형태로 제공되며 4°C 보관. 신경세포 시냅스 및 신경내분비 종양 연구용에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | rSYP/4654 |
| Immunogen | Recombinant fragment (around aa 224–313) of human Synaptophysin (SYP) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Synaptophysin is a calcium-binding and integral membrane glycoprotein present in presynaptic vesicles of almost all neurons. It has four transmembrane domains and forms a complex with dynamin at high calcium concentrations, suggesting a role in synaptic vesicle endocytosis. Synaptophysin is involved in regulating short- and long-term synaptic plasticity and is widely used as a marker for nerve terminals and neuroendocrine tumors. Mutations in the gene can result in mental retardation, X-linked 96.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
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