Thermo Fisher Scientific Synaptophysin Recombinant Mouse Monoclonal Antibody (rSYP, 6856)
Synaptophysin 단백질을 인식하는 재조합 마우스 단클론 항체로, 신경말단 및 신경내분비 종양 마커 연구에 적합. IHC(P) 적용 가능하며, HEK293 세포에서 발현. 고순도 Protein A/G 정제, 안정적 PBS 저장용액 제공.
- 카탈로그번호
- 6855-MSM6-P1
- 판매단위
- pk
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | rSYP, 6856 |
| Immunogen | Recombinant fragment (around aa 224–313) of human Synaptophysin (SYP) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 min at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
Synaptophysin is a calcium-binding integral membrane glycoprotein present in presynaptic vesicles of almost all neurons. It has four transmembrane domains and forms a complex with dynamin at high calcium concentrations, suggesting involvement in synaptic vesicle endocytosis. It also plays a role in the regulation of short-term and long-term synaptic plasticity. Synaptophysin is widely used as a marker for nerve terminals and in differentiating neuroendocrine tumors. Mutations in the gene can result in mental retardation, X-linked 96.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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