Thermo Fisher Scientific Synaptophysin (Neuroendocrine Marker) Monoclonal Antibody (rSYP/4654)
신경내분비 마커 Synaptophysin을 인식하는 Mouse monoclonal 항체. 인간 시료에 반응하며 IHC(P) 및 IHC(PFA)에 적합. 단백질 A/G로 정제된 액상 형태로 제공되며 보존제 무첨가. 연구용으로만 사용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | rSYP/4654 |
| Immunogen | Recombinant fragment (around aa 224–313) of human Synaptophysin (SYP) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Synaptophysin is a calcium-binding integral membrane glycoprotein present in presynaptic vesicles of nearly all neurons. It contains four transmembrane domains and forms a complex with dynamin at high calcium concentrations, suggesting a role in synaptic vesicle endocytosis. Synaptophysin also contributes to the regulation of short- and long-term synaptic plasticity and is widely used as a marker for nerve terminals and neuroendocrine tumor differentiation. Mutations in the gene can result in X-linked mental retardation.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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