Thermo Fisher Scientific Semaphorin-6D Polyclonal Antibody
Rabbit polyclonal antibody targeting Semaphorin-6D for WB and IP applications. Unconjugated liquid form with 1 mg/mL concentration. Predicted reactivity with Mouse and Orangutan. Suitable for axon guidance and semaphorin pathway research.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Between amino acids 1023 and 1073 of human SEMA6D (UniProt ID: Q8NFY4-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with Mouse and Orangutan
Target Information
Semaphorins are a large family of secreted and membrane-associated proteins involved in axon pathfinding, fasciculation, branching, and target selection. All semaphorins possess a Sema domain and a PSI domain in the N-terminal extracellular region.
Additional sequence motifs C-terminal to the Sema domain allow classification into distinct subfamilies. Transmembrane semaphorins, like secreted ones, act as repulsive axon guidance cues.
SEMA6D is a class 6 vertebrate transmembrane semaphorin exhibiting alternative splicing, with six identified transcript variants. Expression of these isoforms is regulated in a tissue- and development-dependent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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