Thermo Fisher Scientific POLR3G Polyclonal Antibody
POLR3G 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. 인간 시료에 반응하며 ICC/IF에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 연구용으로만 사용 가능.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific POLR3G Polyclonal Antibody
Thermo Fisher Scientific POLR3G Polyclonal Antibody
Applications
- Immunocytochemistry (ICC/IF)
Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human POLR3G. Recombinant protein control fragment (Product #RP-104950) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2662074 |
Product Specific Information
Immunogen sequence:
LALKQELRETM KRMPYFIETP EERQDIERYS KRYMKVYKEE WIPDWR
Highest antigen sequence identity to the following orthologs:
- Mouse: 88%
- Rat: 90%
Target Information
DNA-dependent RNA polymerase catalyzes transcription of DNA into RNA using ribonucleoside triphosphates as substrates.
POLR3G is a peripheral component of RNA polymerase III, which synthesizes small RNAs such as 5S rRNA and tRNAs. It may interact with other subunits (RPC3/POLR3C-RPC6/POLR3F-RPC7/POLR3G) to facilitate RNA Pol III binding to the TFIIIB-DNA complex.
POLR3G plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. It acts as a nuclear and cytosolic DNA sensor involved in the innate immune response, detecting non-self dsDNA and transcribing it into dsRNA, which induces type I interferon and NF-κB through the RIG-I pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(해당 제품 이미지가 있을 경우 이 섹션에 배치)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.