Thermo Fisher Scientific NPR3 Polyclonal Antibody
Rabbit polyclonal antibody targeting human NPR3 protein. Validated for IHC and ICC/IF applications. Supplied as liquid, unconjugated form at 0.05 mg/mL. Suitable for research use only, not for diagnostic purposes.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (IHC) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human NPR3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2662620 |
Product Specific Information
Immunogen sequence:
PEFEKFSMEVK SSVEKQGLNM EDYVNMFVEG FHDAILLYVL ALHEVLRAGY SKKDGGKIIQ QTWNRTFEGI AGQVSIDANG DRYGDFSVIA MTDVEAGTQE VIGDYFGKEG RFEMRPNVKY PWGPLKLRID ENRIVEHTNS SPCK
Highest antigen sequence identity to the following orthologs:
- Mouse: 95%
- Rat: 95%
Target Information
This gene encodes one of three natriuretic peptide receptors. Natriuretic peptides regulate blood volume, pressure, pulmonary hypertension, and cardiac function, as well as certain metabolic and growth processes. The encoded receptor mediates clearance of circulating and extracellular natriuretic peptides through receptor endocytosis. Multiple transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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