Thermo Fisher Scientific SERPINB13 Polyclonal Antibody

Applications

Immunocytochemistry (ICC/IF)

• Tested Dilution: 0.25–2 µg/mL

Product Specifications

Product Specific Information

Immunogen sequence:
RGATASQLEEV FHSEKETKSS RIKAEEKEVI ENTEAVHQQF QKFLTEISKL TNDYELNITN RLF

Highest antigen sequence identity to the following orthologs:

• Mouse: 61%
• Rat: 64%

Target Information

Members of the human serpin family regulate a diverse array of serine and cysteine proteinases associated with essential biological processes such as fibrinolysis, coagulation, inflammation, cell mobility, cellular differentiation, and apoptosis. Most serpins are secreted and attain physiologic concentrations in the blood and extracellular fluids. However, a subset of the serpin superfamily, the ov-serpins, also resides intracellularly. Differential display was used to identify a novel serpin (headpin or SERPINB13) that is under expressed in squamous cell cancers of the oral cavity. SERPINB13 is expressed in normal oral mucosal tissue, skin, and cultured keratinocytes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.