Thermo Fisher Scientific NUP214 Polyclonal Antibody
Human NUP214 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC, ICC/IF 등 다양한 면역염색에 사용 가능. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 4°C에서 보관하며 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1250 and 1300 of human Nucleoporin 214 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.50 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with Orangutan, Monkey, Gorilla, and Chimpanzee
Target Information
The nuclear pore complex is a massive structure that spans the nuclear envelope, regulating macromolecule flow between the nucleus and cytoplasm. Nucleoporins are key components of this complex in eukaryotic cells.
This gene encodes an FG-repeat-containing nucleoporin localized to the cytoplasmic face of the nuclear pore complex, essential for proper cell cycle progression and nucleocytoplasmic transport.
The 3′ portion of this gene forms a fusion with the DEK gene on chromosome 6 in a t(6;9) translocation associated with acute myeloid leukemia and myelodysplastic syndrome.
Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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