Thermo Fisher Scientific Phospho-XRCC1 (Ser518, Thr519, Thr523) Polyclonal Antibody
XRCC1 단백질의 Ser518, Thr519, Thr523 인산화 부위를 인식하는 폴리클로날 항체로, 인간 및 생쥐 시료에 반응합니다. IHC 및 IHC(파라핀) 실험에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: 1:50–1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region surrounding residues Ser518, Thr519, and Thr523 of Human X-ray Repair Complementing protein 1 (XRCC1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 50 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Gorilla and Chimpanzee
Target Information
XRCC1 (X-ray cross complementing factor-1) is involved in DNA base excision repair.
It is a 70 kDa protein associated with other DNA repair enzymes, including poly (ADP-ribose) polymerase (PARP), DNA Ligase III, and DNA polymerase beta.
XRCC1 contains a BRCT domain (BRCA1 carboxyl terminus), which mediates protein-protein interaction with DNA ligase III-alpha.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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