Thermo Fisher Scientific PAT1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 386-585 of human APPBP2 (NP_0063712) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PAT1,uniProtId:Q92624-1,ncbiNodeId:9606,antigenRange:386-585,antigenLength:585,antigenImageFileName:PA5-90700_PAT1_Q92624-1_Rabbit.svg,antigenImageFileNamePDP:PA5-90700_PAT1_Q92624-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.7 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2806186

Product Specific Information

Immunogen sequence: LEEIAIDCHN KETEQRLLQE AHDLHLSSLQ LAKKAFGEFN VQTAKHYGNL GRLYQSMRKF KEAEEMHIKA IQIKEQLLGQ EDYEVALSVG HLASLYNYDM NQYENAEKLY LRSIAIGKKL FGEGYSGLEY DYRGLIKLYN SIGNYEKVFE YHNVLSNWNR LRDRQYSVTD ALEDVSTSPQ STEEVVQSFL ISQNVEGPSC; Positive Samples: A-431, HeLa, Jurkat, Raji, Mouse kidney, Mouse brain, Rat kidney, Rat brain; Cellular Location: Cytoplasm, Membrane, Nucleus, Peripheral membrane protein, cytoskeleton

Target Information

The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer`s disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.