
Thermo Fisher Scientific CDH8 Polyclonal Antibody
Rat Cadherin-8 단백질을 인식하는 Rabbit Polyclonal 항체. IHC(P) 및 ELISA에 사용 가능. 보존제가 없는 액상 형태로 제공되며, 단백질 A 및 항원 친화 크로마토그래피로 정제됨. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| ELISA | 1:5,000–1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Rat Cadherin-8/CDH8 Protein (Met1–Met621) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788795 |
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Rat Cadherin-8/CDH8.
Target Information
CDH8 is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins consist of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain.
The extracellular domain includes five subdomains, each containing a cadherin motif, determining the specificity of homophilic cell adhesion activity.
Type II (atypical) cadherins lack the HAV cell adhesion recognition sequence found in type I cadherins. CDH8 is expressed in the brain and is associated with synaptic adhesion, axon outgrowth, and guidance.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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