Thermo Fisher Scientific Human NOD2 Synthetic Peptide
Human NOD2 단백질의 C-말단 14개 아미노산 서열 기반 합성 펩타이드. 항체 PA5-19992의 차단 펩타이드로 사용 가능. 정제된 액상 형태로 제공되며, PBS 버퍼에 0.1% BSA 포함. 연구용으로만 사용.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
Product Specific Information
This peptide corresponds to 14 amino acids near the carboxy terminus of human NOD2.
PEP-0307 can be used as a blocking peptide with polyclonal antibody PA5-19992.
Target Information
NOD2 is a member of the apoptosis regulating protein family that includes caspase recruitment-domains, as well as Apaf-1 and NOD1. It contains two N-terminal CARDs, a nucleotide binding domain (NBD), and multiple C-terminal leucine-rich repeats (LRRs). NOD2 is expressed in monocytes (whereas NOD1 is expressed in multiple tissues). NOD2 plays a role in regulating NF-kappaB, acts as an intracellular receptor for bacterial lipopolysaccharides, and contributes to inflammatory bowel disease (IBD) and Crohn’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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